Thermo Fisher Scientific Licenses Novel Activity-Based Protein Profiling Technology from ActivX Biosciences, Inc.

Monday February 8, 2010

ROCKFORD, Ill., — Thermo Fisher Scientific, the world leader in serving science, today announced it has entered into an exclusive licensing agreement with ActivX Biosciences, Inc. (ActivX) for its Activity-Based Protein Profiling (ABPP) Technology to develop products for sample enrichment, Western blotting and mass spectrometry analysis. The proprietary ABPP Technology can be used for the accurate and broad activity-based profiling of several enzyme families in any biological sample, making it an ideal addition to the Thermo Scientific proteomics product lines.

Under the terms of the agreement, Thermo Fisher will market and sell ABPP-enabled products worldwide under the Thermo Scientific brand. The initial product offerings will include Thermo Scientific Pierce ABPP kits for profiling major enzyme classes including serine hydrolases and proteases, ATPases, kinases and G-proteins. ActivX will retain the use of ABPP for its KiNativ™ mass spectrometry services, Xhibit™ proteomic-based profiling technologies and immunoassay formats.

Chris Budde, vice president and general manager for the Thermo Fisher Scientific Proteomics business explained: “We are delighted to have secured the global license for the ABPP reagents from ActivX. Researchers in the life sciences continue to demand new analytical tools that push the boundaries of performance and data acquisition for their proteomics experiments. This agreement allows us to respond to our customers’ ever evolving needs. We intend to have ABPP products available during 2010, fully supported by our strong sales and marketing organization.”

John Kozarich, chairman and president of ActivX Biosciences, Inc. commented: “Thermo Fisher Scientific is an ideal collaborator for our ABPP reagents and methodologies. Not only do they have outstanding marketing and sales coverage for many life sciences reagents, through their Thermo Scientific Pierce product line, but Thermo Fisher is also a global leader in the development and application of mass spectrometry. This combination allows Thermo Fisher to closely link ABPP technology to their customer requirements with next-generation mass spectrometry equipment for very fast and cost-effective workflows for their customers.”

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